Collaborative Efforts

A study at Walter Reed National Military Medical Center to assess the functionality of the Modular Prosthetic Limb is being expanded to include civilian in addition to military amputees. Several spin-off projects have begun to take off as well. Working with Second Sight, the team is developing the Hybrid Augmented Reality Multimodal Operation Neural Integration Environment—HARMONIE—a semiautonomous controller for assistive robotic manipulators and remote devices.

Johns Hopkins Medicine Department of Surgery

  • Dr. Pablo Celnik
    Johns Hopkins University
    The Human Brain Physiology and Stimulation Laboratory
    Focused on studying the mechanisms underlying motor learning and developing interventions to modulate motor function in humans
  • Targeted Muscle Reinnervation (TMR)

Oregon Health & Science University (OHSU) Department of Surgery

  • Dr. Albert Chi
    Oregon Health & Science University
    • Associate Professor of Surgery, OHSU
    • Medical Director, OHSU Targeted Muscle Reinnervation Program
    • Research and Exploratory Development Department, Johns Hopkins Applied Physics Laboratory
    • Commander, United States Navy Reserves

Other Revolutionizing Prosthetics Related Efforts

California Institute of Technology (Caltech) and Los Amigos Rancho Rehabilitation Research Institute, Inc. (LAREI)

Walter Reed National Military Medical Center (through the Henry M. Jackson Foundation for the Advancement of Military Medicine)

Related Clinical Trials

Search Clinical Trials

NIH-Sponsored Research

Clinician Resources

With 17 degrees of freedom and more than 100 sensors in the hand and upper arm, the Modular Prosthetic Limb (MPL) is the world’s most sophisticated upper-extremity prosthesis. There are currently six MPLs being used for research purposes across the United States, with four more in development. Because of the limited quantities of the device, APL has developed a virtual-reality MPL that runs in the Virtual Integration Environment (VIE). The VIE was developed to make the transition from a virtual training environment to the physical world with the actual MPL as seamless as possible, thus facilitating patient training for optimal control of the prosthetic limb. The VIE translates control signals into limb movements and displays a virtual model of these movements. In this environment, patients can test-drive limbs and provide feedback while still in the recovery stage or while a prosthetic arm is manufactured and fitted. The clinician interface to the VIE allows limb configuration parameters to be tuned for each patient in order to achieve maximum performance.

APL provides the VIE to clinicians and researchers through a no-cost licensing agreement. As of June 2014, sixteen institutions across the world have signed these agreements in applications focused on improvements in myoelectric, electrocorticographic, and cortical control open-loop and closed-loop studies.

Recommended Reading

A Real-Time Virtual Integration Environment for Neuroprosthetics and Rehabilitation (Johns Hopkins APL Technical Digest, Volume 30, Issue 3, pp. 198–206, 2011)

APL Celebrates 80 Years of

Game-Changing Impact

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80th anniversary