Heba Mostafa (left), assistant professor of pathology at Johns Hopkins Medicine, joins APL biologists Tom Mehoke (center) and Peter Thielen as the team initiates a sequencing of the genome of the SARS-CoV-2 virus, which causes COVID-19.

Biology and Bioengineering

Unlocking the power of biology and bioengineering for biodefense and biosecurity

We work to measure, understand, and harness biological systems and processes to drive innovation and enable new capabilities to address critical challenges to national security and human health. Our expertise spans the domains of biochemistry, molecular biology, virology, microbiology, plant biology, marine biology, genomics, bioinformatics, microfluidics, and computational biology.

Related Projects

A researcher experiments in APL’s biomanufacturing lab. (Credit: Johns Hopkins APL)

Advancing Biomanufacturing for National Security

Researchers at APL are combining their technical expertise, creativity, and national security acumen to put biomanufacturing to work to make supply chains more secure, strengthen the defense industrial base, and produce materials wherever and whenever.
Learn more about Advancing Biomanufacturing for National Security
Johns Hopkins APL's Rotating Drum System

Biological Threat Analysis

APL is developing innovative ways to evaluate biological threats in a natural environment.
Learn more about Biological Threat Analysis
Hayley DeHart, a genomics research scientist at APL, loads water samples into a sequencer while on board a ship during the team’s trip to Monterey Bay.

Enlisting eDNA to Understand Ecosystems

APL researchers are using genetic information to observe animals, plants, and microbes in their natural environments, and pioneering environmental DNA (eDNA) analysis methods to study marine ecosystems that the world relies on as the foundation of global food webs.
Learn more about Enlisting eDNA to Understand Ecosystems
Raphael Norman-Tenazas, neuro-AI researcher, tests a robot navigation strategy inspired by the fruit fly connectome.

Neuroscience-Inspired Artificial Intelligence

Developing next-generation learning algorithms that draw inspiration from biological nervous systems to revolutionize intelligent systems.
Learn more about Neuroscience-Inspired Artificial Intelligence
Coral fragments housed in APL’s NAMI facility.

Reversing the Loss of Coral Reefs

Recognizing the need to safeguard America’s coastlines and the value natural structures play in their protection, APL researchers are finding ways to use materials science to support coral reef growth and restoration.
Learn more about Reversing the Loss of Coral Reefs

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