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2018

Use of deep learning for detailed severity characterization and estimation of 5-year risk among patients with age-related macular degeneration


Abstract

Although deep learning (DL) can identify the intermediate or advanced stages of age-related macular degeneration (AMD) as a binary yes or no, stratified gradings using the more granular Age-Related Eye Disease Study (AREDS) 9-step detailed severity scale for AMD provide more precise estimation of 5-year progression to advanced stages. The AREDS 9-step detailed scale's complexity and implementation solely with highly trained fundus photograph graders potentially hampered its clinical use, warranting development and use of an alternate AREDS simple scale, which although valuable, has less predictive ability.

Citation

article: Burlina_2018 doi: 10.1001/jamaophthalmol.2018.4118 url: https://doi.org/10.1001/jamaophthalmol.2018.4118 year: 2018 month: dec publisher: American Medical Association (AMA) volume: 136 number: 12 pages: 1359 author: Burlina Philippe M. and Joshi Neil and Pacheco Katia D. and Freund David E. and Kong Jun and Bressler Neil M. title: Use of Deep Learning for Detailed Severity Characterization and Estimation of 5-Year Risk Among Patients With Age-Related Macular Degeneration journal: JAMA Ophthalmology

Citation

article: Burlina_2018 doi: 10.1001/jamaophthalmol.2018.4118 url: https://doi.org/10.1001/jamaophthalmol.2018.4118 year: 2018 month: dec publisher: American Medical Association (AMA) volume: 136 number: 12 pages: 1359 author: Burlina Philippe M. and Joshi Neil and Pacheco Katia D. and Freund David E. and Kong Jun and Bressler Neil M. title: Use of Deep Learning for Detailed Severity Characterization and Estimation of 5-Year Risk Among Patients With Age-Related Macular Degeneration journal: JAMA Ophthalmology