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2019

Assessment of Deep Generative Models for High-Resolution Synthetic Retinal Image Generation of Age-Related Macular Degeneration


Abstract

Deep learning (DL) used for discriminative tasks in ophthalmology, such as diagnosing diabetic retinopathy or age-related macular degeneration (AMD), requires large image data sets graded by human experts to train deep convolutional neural networks (DCNNs). In contrast, generative DL techniques could synthesize large new data sets of artificial retina images with different stages of AMD. Such images could enhance existing data sets of common and rare ophthalmic diseases without concern for personally identifying information to assist medical education of students, residents, and retinal specialists, as well as for training new DL diagnostic models for which extensive data sets from large clinical trials of expertly graded images may not exist.

Citation

article: Burlina_2019 doi: 10.1001/jamaophthalmol.2018.6156 url: https://doi.org/10.1001/jamaophthalmol.2018.6156 year: 2019 month: mar publisher: American Medical Association (AMA) volume: 137 number: 3 pages: 258 author: Burlina Philippe M. and Joshi Neil and Pacheco Katia D. and Liu T. Y. Alvin and Bressler Neil M. title: Assessment of Deep Generative Models for High-Resolution Synthetic Retinal Image Generation of Age-Related Macular Degeneration journal: JAMA Ophthalmology

Citation

article: Burlina_2019 doi: 10.1001/jamaophthalmol.2018.6156 url: https://doi.org/10.1001/jamaophthalmol.2018.6156 year: 2019 month: mar publisher: American Medical Association (AMA) volume: 137 number: 3 pages: 258 author: Burlina Philippe M. and Joshi Neil and Pacheco Katia D. and Liu T. Y. Alvin and Bressler Neil M. title: Assessment of Deep Generative Models for High-Resolution Synthetic Retinal Image Generation of Age-Related Macular Degeneration journal: JAMA Ophthalmology